Eastern Cape Glamping Road Trip: Garden Route to Malaria-Free Big Five

Long dinner table set on the deck at Woodbury Tented Camp at sunset over Amakhala Game Reserve

Most safaris start with a flight. This one starts with a full tank of fuel. Here is a 10-day malaria-free road trip from Cape Town along Route 62 and the Garden Route to the Eastern Cape, with Big Five at both ends and the best tented camps, treehouses and glamping stays along the way.

Malaria-Free Glamping in South Africa: Madikwe, Waterberg & Eastern Cape

The Waterberg valley seen from Marataba Safari Lodge in Marakele National Park

Nobody has ever come home from safari saying the antimalarial tablets were the highlight. Here are South Africa’s best malaria-free tented camps in Madikwe, the Waterberg and the Eastern Cape, plus a Karoo option most people overlook, with rates, drive times and who each one suits.